A tertiary alcohol that is cyclohexanol substituted at positions 1 and 2 by 3-methoxyphenyl and dimethylaminomethyl groups respectively.
ChEBI ID: 75722
Member | Definition | Role |
---|---|---|
tramadol | A 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have R-configuration; the (R,R)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. | (R,R)-tramadol |
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 68 (1.99) | 18.7374 |
1990's | 309 (9.06) | 18.2507 |
2000's | 1,033 (30.29) | 29.6817 |
2010's | 1,422 (41.70) | 24.3611 |
2020's | 578 (16.95) | 2.80 |
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 1,151 (30.92%) | 5.53% |
Reviews | 330 (8.86%) | 6.00% |
Case Studies | 350 (9.40%) | 4.05% |
Observational | 46 (1.24%) | 0.25% |
Other | 1,846 (49.58%) | 84.16% |